Statistics No Finasteride 59-71: Statistics With drugs 72+:
Slope(1,1) 0.0321 Slope(1,1) (0.1057)
Growth rate 1.0767 Growth rate 0.7840
Growth rate, %/yr. 7.6668 Growth rate, %/yr. (21.5979)
Doubling time, yrs 9.3832 Doubling time, yrs (2.8487)
Y Intercept(1,2) (1.5459) Y Intercept(1,2) 8.6032
Fit, r^2(3,1) 0.6563 Fit, r^2(3,1) 0.1112
PSA Alkaline
Change Testosterone Calcium Vit D Phosphatase
Index Date Days Years JMP PSA ng/ml Log(PSA) ng/dL mg/dL ng/mL U/L
01/20/96 35084 0.00 59.00 300-720 8.4-10.2 30-100 43-117 Normal
1 10/22/96 35360 0.76 59.76 2.60 0.4150 no finasteride
2 10/21/97 35724 1.75 60.75 2.70 0.10 0.4314 no finasteride
3 10/20/98 36088 2.75 61.75 2.40 (0.30) 0.3802 no finasteride
4 10/19/99 36452 3.75 62.75 3.40 1.00 0.5315 no finasteride
5 11/20/00 36850 4.84 63.84 3.20 (0.20) 0.5051 no finasteride
6 11/06/01 37201 5.80 64.80 3.40 0.20 0.5315 no finasteride
7 11/13/02 37573 6.81 65.81 3.60 0.20 0.5563 no finasteride
8 11/04/03 37929 7.79 66.79 2.40 (1.20) 0.3802 no finasteride
9 12/28/04 38349 8.94 67.94 5.60 3.20 0.7482 no finasteride
10 04/11/05 38453 9.22 68.22 5.20 (0.40) 0.7160 no finasteride
11 09/07/05 38602 9.63 68.63 3.80 (1.40) 0.5798 no finasteride
12 03/15/06 38791 10.15 69.15 3.80 0.00 0.5798 no finasteride
13 01/08/07 39090 10.97 69.97 4.60 0.80 0.6628 no finasteride
14 01/10/08 39457 11.97 70.97 6.10 1.50 0.7853 no finasteride
15 04/16/08 39554 12.24 71.24 7.00 0.90 0.8451 no finasteride
1 03/27/09 39899 13.18 72.18 2.95 (4.05) 0.4698 + 5mg finasteride
2 01/22/10 40200 14.01 73.01 2.83 (0.12) 0.4518 96 + 5mg finasteride
3 04/08/11 40641 15.21 74.21 4.79 1.96 0.6803 + 5mg finasteride
4 07/14/12 41104 16.48 75.48 6.19 1.40 0.7917 99 + 5mg finasteride
5 01/17/13 41291 16.99 75.99 7.92 1.73 0.8987 + 5mg finasteride
6 07/22/13 41477 17.50 76.50 8.03 0.11 0.9047 92 + 5mg finasteride
7 08/02/14 41853 18.53 77.53 25.60 17.57 1.4082 81 + 5mg finasteride
8 08/12/15 42228 19.56 78.56 359.00 333.40 2.5551 362 + 5mg finasteride
9 10/05/15 42282 19.71 78.71 24.20 (334.80) 1.3838 14.00 9.00 29 575 Firmagon only
10 11/03/15 42311 19.79 78.79 1.71 (22.49) 0.2330 8.50 40 183 Firmagon and Xgeva
11 12/02/15 42340 19.87 78.87 1.21 (0.50) 0.0828 9.10 117 Firmagon and Xgeva
12 12/28/15 42366 19.94 78.94 0.93 (0.28) (0.0315) 9.10 52 100 Firmagon and Xgeva
13 01/25/16 42394 20.01 79.01 0.77 (0.16) (0.1135) 8.60 88 Firmagon and Xgeva
14 02/23/16 42423 20.09 79.09 0.74 (0.03) (0.1308) 9.20 88 Firmagon and Xgeva
15 03/21/16 42450 20.17 79.17 0.73 (0.01) (0.1367) 8.90 88 Firmagon and Xgeva
16 04/20/16 42480 20.25 79.25 0.67 (0.06) (0.1739) 8.80 86 Firmagon and Xgeva
17 05/17/16 42507 20.32 79.32 0.66 (0.01) (0.1805) 8.70 86 Firmagon and Xgeva
18 06/14/16 42535 20.40 79.40 0.65 (0.01) (0.1871) 8.90 91 Firmagon and Xgeva
19 06/21/16 42542 20.42 79.42 0.65 0.00 (0.1871) 3.00 Start Lupron
20 07/12/16 42563 20.48 79.48 0.69 0.04 (0.1612) 7.00 9.10 93 Labs
21 08/15/16 42597 20.57 79.57 0.85 0.16 (0.0706) 8.00 8.80 94 Labs
22 09/13/16 42626 20.65 79.65 0.72 (0.13) (0.1427) 5.00 9.20 86 Lupron+Xgeva, 9/20
23 12/20/16 42724 20.92 79.92 Labs 12/13/16, Xgeva
PSA Alkaline
Change Testosterone Calcium Vit D Phosphatase
Index Date Days Years JMP PSA ng/ml Log(PSA) ng/dL mg/dL ng/mL U/L
300-720 8.4-10.2 30-100 43-117 Normal
Notes (The plot requires no blanks in PSA columns B-I.)
1. Prostate biopsy on 6/18/08 gave no indication of cancer, only BPH.
2. Began taking 5.0 mg finasteride (generic Proscar) on 7/3/08.
3. Finasteride reduced PSA (and active testosterone, and prostate growth) about 100*(7.0-2.95)/7.0 = 58%
5. Firmagon has reduced PSA by 100*(359-G65)/359 = 99.82%
6. Xgeva and Vitamin D increase bone calcium in the absence of testosterone. Xgeva can cause excessive bone growth.
7. Vitamin D decreased from 5000 to 3000 units per day on 20 Apr 2016.
8. Alkaline phosphatase is a measure of bone breakdown and normal turnover.
9. Increase Calcium from 400 to 800mg per day on 24 May 2016.
10. I came very close to breaking my left wrist by falling in Starved Rock State Park on 7 May 2016.
Prostate cancer: 9/1/2015 2/23/2016 Days
Date 42248 42423 175
Scan1 Scan2
PSA 359.00 0.74